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CJC-1295 + Ipamorelin Blend

GHRH Analogue + GH Secretagogue / Growth Hormone Optimizer

RM 350

FormLyophilized Powder

Storage2-8°C

This product is currently out of stock and cannot be purchased.

Out of Stock

CJC-1295 + Ipamorelin is one of the most widely used and clinically researched growth hormone (GH) peptide blends available. CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to produce and release GH, while Ipamorelin is a selective growth hormone secretagogue (GHS) and ghrelin mimetic that triggers GH pulses without the unwanted hormonal side effects of older GHRPs. Together they act synergistically on two separate receptor pathways (GHRH-R and GHS-R), producing amplified, physiologically natural GH pulses that support muscle growth, fat loss, recovery, anti-aging, and overall metabolic health.

Research Metrics

99.0%Purity

Blend purity verified

2Peptides

GHRH + GHRP synergy

6-8daysHalf-Life

CJC-1295 DAC extended

3-4xGH Increase

Pulse amplitude boost

Mechanism of Action

CJC-1295 binds and activates GHRH receptors (GHRH-R) on somatotroph cells in the anterior pituitary, stimulating GH synthesis and pulsatile secretion. The DAC modification extends its half-life to 6-8 days via covalent albumin binding, providing sustained GHRH-R stimulation between doses. Ipamorelin acts on the ghrelin receptor (GHS-R1a), stimulating GH release through a separate intracellular pathway (cAMP/PKA vs. IP3/PKC). The dual-receptor activation produces supra-additive GH pulse amplitude while preserving the natural pulsatile pattern and feedback regulation of the somatotropic axis.

Scientific Benefits

GH Pulse Amplification — CJC-1295 + Ipamorelin together produce stronger, more sustained GH pulses than either peptide alone, without blunting natural pulsatility.
Lean Muscle Growth — Elevated GH and IGF-1 drive muscle protein synthesis, nitrogen retention, and satellite cell activation for hypertrophy.
Fat Loss — GH-driven lipolysis reduces body fat, particularly visceral adipose tissue, with preferential fat loss during caloric restriction.
Recovery Acceleration — Faster tissue repair, reduced DOMS, and accelerated recovery from training and injury.
Sleep Quality Improvement — GH secretion is highest during deep sleep; the blend amplifies nighttime GH release, deepening sleep architecture and subjective sleep quality.
Anti-aging Effects — Restoring youthful GH levels improves skin quality, bone density, cognitive function, and energy.
No Cortisol or Prolactin Increase — Ipamorelin is highly selective; unlike older GHRPs (GHRP-6, GHRP-2), it does not elevate cortisol or prolactin at therapeutic doses.
Collagen & Joint Support — IGF-1 elevation supports collagen synthesis in tendons, ligaments, and cartilage.
IGF-1 Elevation — Sustained GH increase drives hepatic IGF-1 production, mediating the anabolic and regenerative effects systemically.
Synergistic Mechanism — GHRH-receptor (CJC-1295) and ghrelin receptor (Ipamorelin) activation via distinct pathways creates additive-to-synergistic GH release.

Disclaimer & Usage Notice

GENERAL USAGE NOTICE. The products offered on this website are sold strictly for your own personal purposes. By purchasing, you acknowledge that you are assuming all risks associated with the handling and application of these products.